The association between MCT1 T1470A polymorphism and power-oriented athletic performance
(Die Beziehung zwischen MCT1 T1470A Polymorphismus und schnellkraft-orientierten sportlichen Leistungen)
The purpose of this study was to investigate the effects of the MCT1 T1470A polymorphism (rs1049434) on power-oriented performance and lactate concentration during or after cycling sprints in Japanese wrestlers. Participants (199 wrestlers and 649 controls) were genotyped for the MCT1 T1470A genotype (rs1049434) using the TaqMan® Assay. All wrestlers were international (n=77) or national (n=122) level athletes. Among them, 46 wrestlers performed 2 anaerobic performance tests, a 30-s Wingate Anaerobic test (WAnT) and a series of 10 maximal effort 10-s sprints on a cycle ergometer. Blood lactate levels were measured before, during, and after the tests. In the A-allele recessive model (AA vs. TA+TT), the frequency of the AA genotype was significantly higher in all wrestlers than in controls (p=0.037). Wrestlers with AA genotype had lower blood lactate concentrations than those with TA+TT genotype at 10 min after the WAnT and following the 5th and the final set of repeated cycling sprints (p<0.05). The AA genotype of the MCT1 T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s WAnT and during intermittent sprint tests in Japanese wrestlers.
© Copyright 2017 International Journal of Sports Medicine. Thieme. Alle Rechte vorbehalten.
Schlagworte: | Ringen Leistungssport Laktat Blut Leistung anaerob männlich Genetik Schnellkraft Explosivkraft Test |
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Notationen: | Biowissenschaften und Sportmedizin Kampfsportarten |
DOI: | 10.1055/s-0042-117113 |
Veröffentlicht in: | International Journal of Sports Medicine |
Veröffentlicht: |
2017
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Jahrgang: | 38 |
Heft: | 1 |
Seiten: | 76-80 |
Dokumentenarten: | Artikel |
Sprache: | Englisch |
Level: | hoch |