The ongoing global pandemic brought on by the spread of the novel coronavirus SARS-CoV-2 is having profound effects on human health and well-being. With no viable vaccine presently available and the virus being rapidly transmitted, governments and national health authorities have acted swiftly, recommending `lockdown` policies and/or various levels of social restriction/isolation to attenuate the rate of infection. An immediate consequence of these strategies is reduced exposure to daylight, which can result in marked changes in patterns of daily living such as the timing of meals, and sleep. These disruptions to circadian biology have severe cardiometabolic health consequences for susceptible individuals. We discuss the consequences of reductions in patterns of daily physical activity and the resulting energy imbalance induced by periods of isolation, along with several home-based strategies to maintain cardiometabolic health in the forthcoming months. Key Points The global pandemic caused by the novel coronavirus SARS-CoV-2 may lead to deleterious health effects through reductions in daily energy expenditure, uncompensated energy intake, altered sleep, and a decrease in levels of voluntary physical activity. Such behaviour patterns are likely to exacerbate the present public health crisis created by low levels of voluntary physical activity and the subsequent consequences for cardiometabolic health. Some of the negative health outcomes that result from COVID-19 related isolation can be minimised by implementing graded lifestyle strategies to reduce sitting time, encourage structured physical activity, and maintain good dietary practices.
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