Serum androgen profile and physical performance in women Olympic athletes
(Serum-Androgen-Profil und körperliche Leistung von Olympiateilnehmerinnen)
Background: The role of endogenous androgens for body composition and physical performance in women athletes is still not elucidated.
Aim: To examine the serum androgen profile in relation to body composition and physical performance in women Olympic athletes and to compare endocrine variables and body composition to controls.
Study design: Cross-sectional study, conducted between 2011 and 2015 at the Women`s Health Research Unit, Karolinska University Hospital, Stockholm.
Methods: Swedish women Olympic athletes (n=106) and age-matched and body mass index-matched sedentary controls (n=117) were included in the study. Blood sampling was performed in a rested, fasting state for the measurement of serum androgens and their metabolites by liquid chromatography-tandem mass spectrometry. Body composition was determined by dual-energy X-ray absorptiometry (controls n=100, athletes n=65). The athletes performed standardised performance tests (n=59) (squat jump (SJ) and countermovement jump (CMJ).
Results: The athletes demonstrated significantly higher levels of the precursor androgens dehydroepiandrosterone (DHEA) and 5-androstene-3ß, 17ß-diol (5-DIOL) and the metabolite etiocholanolone glucuronide (Etio-G), significantly lower levels of estrone (p<0.05, respectively), higher bone mineral density (p<0.001) and more lean mass (p<0.001) compared with controls. Serum levels of DHEA, 5-DIOL and Etio-G correlated positively to lean mass variables and physical performance in the athletes. DHEA and lean mass legs explained 66% of the variance in SJ, whereas lean mass explained 52% of the variance in CMJ.
Conclusions: The present data suggest that endogenous androgens are associated with a more anabolic body composition and enhanced performance in women athletes. These results are of importance for the current discussion regarding hyperandrogenism in women athletes.
© Copyright 2017 British Journal of Sports Medicine. BMJ Publishing Group Ltd of the BMA. Alle Rechte vorbehalten.
Schlagworte: | Sportmedizin Untersuchungsmethode Test Blut Serum Hormon männlich weiblich Analyse Verletzung Statistik |
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Notationen: | Biowissenschaften und Sportmedizin |
Tagging: | BMI androgen |
DOI: | 10.1136/bjsports-2017-097582 |
Veröffentlicht in: | British Journal of Sports Medicine |
Veröffentlicht: |
2017
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Jahrgang: | 51 |
Heft: | 17 |
Seiten: | 1301-1308 |
Dokumentenarten: | Artikel |
Sprache: | Englisch |
Level: | hoch |